2026
Gonzalez-Aponte MF, Salvatore SV, Damato AR, Katumba RG, Talcott GR, Butt OH, Campian JL, Luo J, Rubin JB, Walch OJ, Herzog ED. Daily locomotor activity declines with tumor growth and disease progression in glioblastoma. JCI Insight. 2025 Nov 25;11(1):e194582. doi: 10.1172/jci.insight.194582. PMID: 41289012; PMCID: PMC12890484.
2025
Gonzalez-Aponte MF, Huang Y, Leidig WA, Simon T, Butt OH, Ruben MD, Kim AH, Rubin JB, Herzog ED, Walch OJ. Circadian variation in MGMT promoter methylation and expression predicts sensitivity to temozolomide in glioblastoma. J Neurooncol. 2025 Oct 22;176(1):36. doi: 10.1007/s11060-025-05242-3. PMID: 41123669; PMCID: PMC12546296.
Gonzalez-Aponte MF, Damato AR, Katumba RGN, Talcott GR, Campian JL, Butt OH, Ruben MD, Rubin JB, Herzog ED, Walch OJ. Tracking Daily Variations in Rest-Wake to Guide Personalized Timing of Temozolomide for High-Grade Glioma Patients. J Biol Rhythms. 2025 Aug;40(4):320-329. doi: 10.1177/07487304251336826. Epub 2025 May 27. PMID: 40432273; PMCID: PMC12263323.
Pferdehirt L, Damato AR, Lenz KL, Gonzalez-Aponte MF, Palmer D, Meng QJ, Herzog ED, Guilak F. A synthetic chronogenetic gene circuit for programmed circadian drug delivery. Nat Commun. 2025 Feb 7;16(1):1457. doi: 10.1038/s41467-025-56584-5. PMID: 39920119; PMCID: PMC11806060.
Gonzalez-Aponte MF, Damato AR, Simon T, Aripova N, Darby F, Jeon MS, Luo J, Rubin JB, Herzog ED. Daily glucocorticoids promote glioblastoma growth and circadian synchrony to the host. Cancer Cell. 2025 Jan 13;43(1):144-160.e7. doi: 10.1016/j.ccell.2024.11.012. Epub 2024 Dec 12. PMID: 39672168; PMCID: PMC11732716.
2024
Gonzalez-Aponte MF, Damato AR, Trebucq LL, Simon T, Cárdenas-García SP, Cho K, Patti GJ, Golombek DA, Chiesa JJ, Rubin JB, Herzog ED. Circadian regulation of MGMT expression and promoter methylation underlies daily rhythms in TMZ sensitivity in glioblastoma. J Neurooncol. 2024 Feb;166(3):419-430. doi: 10.1007/s11060-023-04535-9. Epub 2024 Jan 26. PMID: 38277015; PMCID: PMC11301575.
2023
Hastings MH, Brancaccio M, Gonzalez-Aponte MF, Herzog ED. Circadian Rhythms and Astrocytes: The Good, the Bad, and the Ugly. Annu Rev Neurosci. 2023 Jul 10;46:123-143. doi: 10.1146/annurev-neuro-100322-112249. Epub 2023 Mar 28. PMID: 36854316; PMCID: PMC10381027.